AMD Instinct MI210 vs AMD Instinct MI300X

A side-by-side comparison of specs, capabilities, and use cases.

By Fredoline Eruo·Last updated Jun 12, 2026·AMD Instinct MI210·AMD Instinct MI300X
SpecAMD Instinct MI210AMD Instinct MI300X
VRAM64 GB192 GB
Vendoramdamd
Tierworkstationworkstation
Power draw300 W750 W
Released20222023
Street price
CUDANoNo
ROCmYesYes
Metal / MLXNoNo

Frequently asked

Which is better, AMD Instinct MI210 or AMD Instinct MI300X?

Neither is universally better — pick based on your specific need. AMD Instinct MI210 suits some workloads, AMD Instinct MI300X suits others. The spec table above shows where each wins.

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