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OP·Fredoline Eruo
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RUNLOCALAI · v38
hardwares / AMD Instinct MI355X vs NVIDIA B200

AMD Instinct MI355X vs NVIDIA B200

A side-by-side comparison of specs, capabilities, and use cases.

By Fredoline Eruo·Last updated Jun 12, 2026·AMD Instinct MI355X·NVIDIA B200
SpecAMD Instinct MI355XNVIDIA B200
VRAM288 GB192 GB
Vendoramdnvidia
Tierworkstationworkstation
Power draw1000 W1000 W
Released20252024
Street price——
CUDANoYes
ROCmYesNo
Metal / MLXNoNo

Frequently asked

Which is better, AMD Instinct MI355X or NVIDIA B200?

Neither is universally better — pick based on your specific need. AMD Instinct MI355X suits some workloads, NVIDIA B200 suits others. The spec table above shows where each wins.

Reviewed by RunLocalAI Editorial. See our editorial policy.